Histiocytic Sarcoma In a 4-Year-Old Female Spayed Ferret: Our Case of the Month 2021
Dr. Cathy Jarrett, owner of Potomac Mobile Veterinary Ultrasound, performed the ultrasound and FNA procedures on Olive, a very sick little ferret. Histiocytic sarcoma is described in the literature as a rare, very aggressive hematopoietic tumor of histiocytes, in ferrets most commonly found in the spleen but can be elsewhere. Performing the FNA procedure in two sites as Dr Jarrett did here increased the probability of obtaining the information needed for Dr. Mary Ann McKissick and the team at Buckeystown Veterinary Hospital, allowing them to expeditiously create a care plan with Olive's family. Interpretation of images by: Eric C Lindquist BS, DMV (Italy), DABVP.
Weight loss, diarrhea, decreased appetite, occasional weakness. Glucose checks have been consistently in the low 60s. HCT over 60%, ALT 299, AST 141, BG 61. Recheck BG 64.
Spleen: The spleen revealed an expansive target type nodule that measured 1.8 cm at the cranial pole. The spleen was otherwise enlarged with scalloping contour with free fluid.
Pancreas: The left limb of the pancreas revealed heterogenous parenchymal changes with a hypoechoic nodule or overlying lymph node measuring 0.74 cm.
Gastrointestinal: The gastrointestinal tract revealed diffuse, hyperechoic fogging or overlay throughout the small intestine as well as areas of mucosal striations and speckling. This striation + fogging effect appeared to exclusively affect the mucosal layer with the submucosa, muscularis and serosa left in-act. Reactive mesentery was present associated with the serosa indicative of active inflammation. This is most consistent with protein losing enteropathy/lymphangectasia. Full thickness biopsies or endoscopic guided biopsies would be ideal to confirm. A cluster of mesenteric lymph nodes with distorted architecture was noted. The largest of which measured 2.04 x 1.02 cm.
Free Abdomen: Minor areas of free fluid was present.